Our newly published review explores how tumor-derived EVs contribute to premetastatic niche formation through immune and stromal reprogramming—and whether these same vesicles could be exploited to image these early changes using PET/SPECT, MRI, CT, and optical approaches.
The field is still largely preclinical, but the intersection of EV-mediated immune modulation, metastasis, and molecular imaging is particularly interesting.
I’m would love to hear perspectives from the community.